Which infection is most common in terminal complement deficiency?

Unlock all questions

This demo includes only 20 questions. Upgrade to access hundreds of questions, flashcards, exam simulations, and disable ads.

Full question bankExam simulationsFlashcards
From $25.99Unlock all

Enhance your Step 2 prep with AMBOSS 200 HY Concepts. Dive into flashcards and MCQs, each with detailed explanations. Ace your exam with confidence!

Multiple Choice

Which infection is most common in terminal complement deficiency?

Explanation:
Terminal complement deficiency impairs formation of the membrane attack complex, which is especially important for killing Neisseria species. Without MAC-mediated lysis, Neisseria meningitidis (and Neisseria gonorrhoeae) can cause invasive infections such as meningococcemia and meningitis more readily. This makes Neisseria infections the most characteristic and common risk in individuals with terminal complement deficiencies. Other bacteria like Staphylococcus aureus, E. coli, or Streptococcus pneumoniae can cause infections in many settings, but they are not specifically tied to MAC deficiency in the same way Neisseria is.

Terminal complement deficiency impairs formation of the membrane attack complex, which is especially important for killing Neisseria species. Without MAC-mediated lysis, Neisseria meningitidis (and Neisseria gonorrhoeae) can cause invasive infections such as meningococcemia and meningitis more readily. This makes Neisseria infections the most characteristic and common risk in individuals with terminal complement deficiencies. Other bacteria like Staphylococcus aureus, E. coli, or Streptococcus pneumoniae can cause infections in many settings, but they are not specifically tied to MAC deficiency in the same way Neisseria is.

More Multiple Choice Questions
Subscribe

Get the latest from Passetra

You can unsubscribe at any time. Read our privacy policy