Neurofibromatosis type 2 is most characteristically associated with which combination of tumors?

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Multiple Choice

Neurofibromatosis type 2 is most characteristically associated with which combination of tumors?

Explanation:
Neurofibromatosis type 2 is defined by tumors of the nervous system, especially bilateral vestibular schwannomas, along with other CNS tumors such as meningiomas and ependymomas. Cataracts, particularly early/posterior subcapsular ones, are a common associated finding. So the combination of schwannomas, meningiomas, ependymomas, and early onset cataracts best fits NF2. By contrast, café-au-lait spots and neurofibromas point to NF1; optic nerve gliomas are more characteristic of NF1; CFTR mutations are unrelated to these conditions.

Neurofibromatosis type 2 is defined by tumors of the nervous system, especially bilateral vestibular schwannomas, along with other CNS tumors such as meningiomas and ependymomas. Cataracts, particularly early/posterior subcapsular ones, are a common associated finding. So the combination of schwannomas, meningiomas, ependymomas, and early onset cataracts best fits NF2. By contrast, café-au-lait spots and neurofibromas point to NF1; optic nerve gliomas are more characteristic of NF1; CFTR mutations are unrelated to these conditions.

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